In TMD, headaches occur due to improper occlusion (teeth bite). Regular use of improper bite leads to headaches that do not respond to traditional treatments or medicines.

In OSA, patients generally complain of headaches on waking up (due to the physiological response of clenching/grinding due to OSA) that may last throughout the day. Headache occurs due to lack of oxygen in the blood stream. This is because of inability of the patient to breathe in deeply or get enough oxygen. This leads to insufficiency of oxygen and also decreased exhalation of carbon dioxide. Thus, leading to headache as the person wakes up in the morning. With the Orthotic appliance on, the bite is more physiological allowing smooth flow of gases in the respiratory system. The Holistic Dental & Medical Insitute provides headache and migraine treatments after proper diagnosis.